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Structure factors have been supplied for datablock(s) KL_05_046_THF

THIS REPORT IS FOR GUIDANCE ONLY. IF USED AS PART OF A REVIEW PROCEDURE FOR PUBLICATION, IT SHOULD NOT REPLACE THE EXPERTISE OF AN EXPERIENCED CRYSTALLOGRAPHIC REFEREE.
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Structure factor report

Datablock: KL_05_046_THF
Bond precision: C-C = 0.0529 A Wavelength=0.71073
Cell: a=31.527(4) b=31.527(4) c=77.177(6)
alpha=90 beta=90 gamma=120
Temperature: 100 K
Calculated Reported
Volume 66433(18) 66433(17)
Space group R -3 c R -3 c :H
Hall group -R 3 2"c -R 3 2"c
Moiety formula 2(C240 H150 Cu12 N18 O96), 3(C40 H28 N2) [+ solvent] 2(C240 H150 Cu12 N18 O96), 3(C40 H28 N2)
Sum formula C600 H384 Cu24 N42 O192 [+ solvent] C600 H384 Cu24 N42 O192
Mr 12778.68 12778.43
Dx,g cm-3 0.958 0.958
Z 3 3
Mu (mm-1) 0.626 0.626
F000 19530.0 19530.0
F000' 19562.57
h,k,lmax 24,24,59 24,24,59
Nref 3525 3516
Tmin,Tmax 0.883,0.927 0.440,0.745
Tmin' 0.883
Correction method= # Reported T Limits: Tmin=0.440 Tmax=0.745 AbsCorr = MULTI-SCAN
Data completeness= 0.997 Theta(max)= 15.863
R(reflections)= 0.1564( 1282) wR2(reflections)= 0.3703( 3516)
S = 1.216 Npar= 991

The following ALERTS were generated. Each ALERT has the format
       test-name_ALERT_alert-type_alert-level.
Click on the hyperlinks for more details of the test.

Alert level A THETM01_ALERT_3_A The value of sine(theta_max)/wavelength is less than 0.550 Calculated sin(theta_max)/wavelength = 0.3846
Author Response: Due to disorder (hot crystal syndrome) and high mosaicity no data was observed bejond a resolution of 1.2 Angstrom.
PLAT023_ALERT_3_A Resolution (too) Low [sin(theta)/Lambda < 0.6]..       0.38 Ang-1 
Author Response: see above
PLAT088_ALERT_3_A Poor Data / Parameter Ratio ....................       3.55 Note  
Author Response: due to disorder, as weel as what is said above, amount of data was limited.

Alert level B PLAT026_ALERT_3_B Ratio Observed / Unique Reflections (too) Low .. 36% Check PLAT082_ALERT_2_B High R1 Value .................................. 0.16 Report PLAT084_ALERT_3_B High wR2 Value (i.e. > 0.25) ................... 0.37 Report PLAT341_ALERT_3_B Low Bond Precision on C-C Bonds ............... 0.05286 Ang. PLAT420_ALERT_2_B D-H Bond Without Acceptor O15 --H15A . Please Check PLAT420_ALERT_2_B D-H Bond Without Acceptor O15 --H15B . Please Check
Alert level C RINTA01_ALERT_3_C The value of Rint is greater than 0.12 Rint given 0.173 PLAT020_ALERT_3_C The Reported Value of Rint is Greater Than 0.12 0.173 Report PLAT220_ALERT_2_C NonSolvent Resd 1 C Ueq(max)/Ueq(min) Range 3.6 Ratio PLAT241_ALERT_2_C High MainResAtom Ueq as Compared to Neighbours O1 Check
And 7 other PLAT241 Alerts More ...

PLAT241_ALERT_2_C High MainResAtom Ueq as Compared to Neighbours O2 Check PLAT241_ALERT_2_C High MainResAtom Ueq as Compared to Neighbours C6 Check PLAT241_ALERT_2_C High MainResAtom Ueq as Compared to Neighbours C8 Check PLAT241_ALERT_2_C High MainResAtom Ueq as Compared to Neighbours C13 Check PLAT241_ALERT_2_C High MainResAtom Ueq as Compared to Neighbours C15 Check PLAT241_ALERT_2_C High MainResAtom Ueq as Compared to Neighbours C19 Check PLAT241_ALERT_2_C High MainResAtom Ueq as Compared to Neighbours C40 Check

PLAT242_ALERT_2_C Low MainResAtom Ueq as Compared to Neighbours Cu1 Check
And 7 other PLAT242 Alerts More ...

PLAT242_ALERT_2_C Low MainResAtom Ueq as Compared to Neighbours O16 Check PLAT242_ALERT_2_C Low MainResAtom Ueq as Compared to Neighbours C1 Check PLAT242_ALERT_2_C Low MainResAtom Ueq as Compared to Neighbours C7 Check PLAT242_ALERT_2_C Low MainResAtom Ueq as Compared to Neighbours C9 Check PLAT242_ALERT_2_C Low MainResAtom Ueq as Compared to Neighbours C12 Check PLAT242_ALERT_2_C Low MainResAtom Ueq as Compared to Neighbours C18 Check PLAT242_ALERT_2_C Low MainResAtom Ueq as Compared to Neighbours C24 Check

PLAT260_ALERT_2_C Large Average Ueq of Residue Including Cu1 0.143 Check PLAT260_ALERT_2_C Large Average Ueq of Residue Including N4 0.150 Check PLAT309_ALERT_2_C Single Bonded Oxygen (C-O > 1.3 Ang) ........... O9B Check PLAT360_ALERT_2_C Short C(sp3)-C(sp3) Bond C37 - C38 . 1.39 Ang. PLAT360_ALERT_2_C Short C(sp3)-C(sp3) Bond C38 - C39 . 1.41 Ang. PLAT790_ALERT_4_C Centre of Gravity not Within Unit-Cell: Resd. # 1 Note C240 H150 Cu12 N18 O96 PLAT905_ALERT_3_C Negative K value in the Analysis of Variance ... -33.618 Report
And 2 other PLAT905 Alerts More ...

PLAT905_ALERT_3_C Negative K value in the Analysis of Variance ... -4.825 Report PLAT905_ALERT_3_C Negative K value in the Analysis of Variance ... -0.644 Report

PLAT911_ALERT_3_C Missing FCF Refl Between Thmin & STh/L= 0.385 7 Report 0 7 2, -1 2 3, -1 4 4, -3 4 5, -1 5 6, -2 3 7, -3 7 8,
Alert level G PLAT002_ALERT_2_G Number of Distance or Angle Restraints on AtSite 106 Note PLAT003_ALERT_2_G Number of Uiso or U(i,j) Restrained non-H-Atoms 122 Report PLAT007_ALERT_5_G Number of Unrefined Donor-H Atoms .............. 4 Report H15A H15B H4 H5A PLAT083_ALERT_2_G SHELXL Second Parameter in WGHT Unusually Large 5000.00 Why ? PLAT160_ALERT_4_G max(sig)/min(sig) ratio x,y,z > 3 for C25 3.40 Check
And 22 other PLAT160 Alerts More ...

PLAT160_ALERT_4_G max(sig)/min(sig) ratio x,y,z > 3 for C26 3.06 Check PLAT160_ALERT_4_G max(sig)/min(sig) ratio x,y,z > 3 for C28 3.06 Check PLAT160_ALERT_4_G max(sig)/min(sig) ratio x,y,z > 3 for C29 3.06 Check PLAT160_ALERT_4_G max(sig)/min(sig) ratio x,y,z > 3 for C31 3.06 Check PLAT160_ALERT_4_G max(sig)/min(sig) ratio x,y,z > 3 for C32 4.09 Check PLAT160_ALERT_4_G max(sig)/min(sig) ratio x,y,z > 3 for C36 4.09 Check PLAT160_ALERT_4_G max(sig)/min(sig) ratio x,y,z > 3 for N1 8.16 Check PLAT160_ALERT_4_G max(sig)/min(sig) ratio x,y,z > 3 for O9 7.34 Check PLAT160_ALERT_4_G max(sig)/min(sig) ratio x,y,z > 3 for O10 6.12 Check PLAT160_ALERT_4_G max(sig)/min(sig) ratio x,y,z > 3 for C125 4.09 Check PLAT160_ALERT_4_G max(sig)/min(sig) ratio x,y,z > 3 for C126 3.40 Check PLAT160_ALERT_4_G max(sig)/min(sig) ratio x,y,z > 3 for C130 3.27 Check PLAT160_ALERT_4_G max(sig)/min(sig) ratio x,y,z > 3 for C131 4.09 Check PLAT160_ALERT_4_G max(sig)/min(sig) ratio x,y,z > 3 for C132 3.40 Check PLAT160_ALERT_4_G max(sig)/min(sig) ratio x,y,z > 3 for C136 3.40 Check PLAT160_ALERT_4_G max(sig)/min(sig) ratio x,y,z > 3 for N1B 5.00 Check PLAT160_ALERT_4_G max(sig)/min(sig) ratio x,y,z > 3 for O9B 5.00 Check PLAT160_ALERT_4_G max(sig)/min(sig) ratio x,y,z > 3 for O10B 5.00 Check PLAT160_ALERT_4_G max(sig)/min(sig) ratio x,y,z > 3 for C60 3.06 Check PLAT160_ALERT_4_G max(sig)/min(sig) ratio x,y,z > 3 for C61 3.06 Check PLAT160_ALERT_4_G max(sig)/min(sig) ratio x,y,z > 3 for C62 3.06 Check PLAT160_ALERT_4_G max(sig)/min(sig) ratio x,y,z > 3 for C52 3.27 Check

PLAT171_ALERT_4_G The CIF-Embedded .res File Contains EADP Records 3 Report PLAT172_ALERT_4_G The CIF-Embedded .res File Contains DFIX Records 10 Report PLAT174_ALERT_4_G The CIF-Embedded .res File Contains FLAT Records 9 Report PLAT175_ALERT_4_G The CIF-Embedded .res File Contains SAME Records 13 Report PLAT176_ALERT_4_G The CIF-Embedded .res File Contains SADI Records 2 Report PLAT178_ALERT_4_G The CIF-Embedded .res File Contains SIMU Records 2 Report PLAT186_ALERT_4_G The CIF-Embedded .res File Contains ISOR Records 2 Report PLAT188_ALERT_3_G A Non-default SIMU Restraint Value has been used 0.0200 Report PLAT188_ALERT_3_G A Non-default SIMU Restraint Value has been used 0.0100 Report PLAT191_ALERT_3_G A Non-default SADI Restraint Value has been used 0.0050 Report PLAT191_ALERT_3_G A Non-default SADI Restraint Value has been used 0.0100 Report PLAT299_ALERT_4_G Atom Site Occupancy Constrained at ............. 0.5 Check O9 O9B O10 O10B O11A O11B O12A O12B O13A O13B O14A O14B N1 N1B N2A N2B N3A N3B C25 C26 C27 C28 C29 C30 C31 C32 C33 C34 C35 C36 C125 C126 C127 C128 C129 C130 C131 C132 C133 C134 C135 C136 H27 H29 H33 H35 H127 H129 H133 H135 PLAT299_ALERT_4_G Atom Site Occupancy Constrained at ............. 0.25 Check N4 N5 C45 C46 C47 C48 C49 C50 C51 C52 C53 C54 C55 C56 C57 C58 C59 C60 C61 C62 C63 C64 C65 C66 C67 C68 C153 C154 C155 C156 C157 C158 C159 C160 C161 C162 C163 C164 C165 C166 C167 C168 H4 H5A H45A H45B H47 H48 H50 H51 H52A H52B H53 H54 H58 H59 H64 H65 H66 H67 H68 H153 H154 H158 H159 H160 H164 H165 H167 H168 PLAT301_ALERT_3_G Main Residue Disorder ..............(Resd 1) 34% Note PLAT302_ALERT_4_G Anion/Solvent/Minor-Residue Disorder (Resd 2) 100% Note PLAT304_ALERT_4_G Non-Integer Number of Atoms in ..... (Resd 2) 17.50 Check PLAT371_ALERT_2_G Long C(sp2)-C(sp1) Bond C4 - C8 . 1.46 Ang. PLAT371_ALERT_2_G Long C(sp2)-C(sp1) Bond C12 - C16 . 1.45 Ang. PLAT411_ALERT_2_G Short Inter H...H Contact H23 ..H164 . 2.03 Ang. 2/3-x+y,1/3+y,-1/6+z = 29_555 Check PLAT411_ALERT_2_G Short Inter H...H Contact H40B ..H159 . 1.91 Ang. 2/3-x+y,1/3+y,-1/6+z = 29_555 Check PLAT432_ALERT_2_G Short Inter X...Y Contact O14A ..C38 . 2.93 Ang. 1-x,1-y,2-z = 19_667 Check PLAT432_ALERT_2_G Short Inter X...Y Contact O14B ..C38 . 2.97 Ang. 1-x,1-y,2-z = 19_667 Check PLAT432_ALERT_2_G Short Inter X...Y Contact C13 ..C35 . 3.08 Ang. 1/3+y,2/3+x,y/6-z = 16_556 Check PLAT606_ALERT_4_G Solvent Accessible VOID(S) in Crystal Structure ! Info PLAT721_ALERT_1_G Bond Calc 0.97000, Rep 0.99000 Dev... 0.02 Ang. C39 -H39B 1_555 1_555 ........ # 202 Check PLAT722_ALERT_1_G Angle Calc 107.00, Rep 108.50 Dev... 1.50 Degree C49 -C52 -H52B 1_555 1_555 1_555 # 238 Check
And 2 other PLAT722 Alerts More ...

PLAT722_ALERT_1_G Angle Calc 108.00, Rep 109.80 Dev... 1.80 Degree C38 -C39 -H39A 1_555 1_555 1_555 # 350 Check PLAT722_ALERT_1_G Angle Calc 112.00, Rep 109.80 Dev... 2.20 Degree C40 -C39 -H39B 1_555 1_555 1_555 # 353 Check

PLAT760_ALERT_1_G CIF Contains no Torsion Angles ................. ? Info PLAT789_ALERT_4_G Atoms with Negative _atom_site_disorder_group # 70 Check PLAT802_ALERT_4_G CIF Input Record(s) with more than 80 Characters 1 Info PLAT811_ALERT_5_G No ADDSYM Analysis: Too Many Excluded Atoms .... 84 Info PLAT822_ALERT_4_G CIF-embedded .res Contains Negative PART Numbers 1 Check PLAT860_ALERT_3_G Number of Least-Squares Restraints ............. 2176 Note PLAT869_ALERT_4_G ALERTS Related to the Use of SQUEEZE Suppressed ! Info PLAT908_ALERT_2_G Max. Perc. Data with I > 2*s(I) per Res.Shell .. 48.43% Note PLAT910_ALERT_3_G Missing FCF Reflection(s) Below Theta(Min)[Deg]= 1.29 Note -1 2 0, 0 1 2, PLAT933_ALERT_2_G Number of HKL-OMIT Records in Embedded .res File 9 Note 0 1 2, -3 4 5, 0 7 2, -1 2 3, -1 2 0, -3 7 8, -1 4 4, -1 5 6, -2 3 7, PLAT941_ALERT_3_G Average HKL Measurement Multiplicity ........... 1.9 Low PLAT955_ALERT_1_G Reported (CIF) and Actual (FCF) Lmax Differ by . 1 Units PLAT969_ALERT_5_G The 'Henn et al.' R-Factor-gap value ........... 2.000 Note Predicted wR2: Based on SigI**2 18.51 or SHELX Weight 30.46 Note PLAT978_ALERT_2_G Number C-C Bonds with Positive Residual Density. 0 Info
3 ALERT level A = Most likely a serious problem - resolve or explain 6 ALERT level B = A potentially serious problem, consider carefully 29 ALERT level C = Check. Ensure it is not caused by an omission or oversight 69 ALERT level G = General information/check it is not something unexpected 6 ALERT type 1 CIF construction/syntax error, inconsistent or missing data 38 ALERT type 2 Indicator that the structure model may be wrong or deficient 20 ALERT type 3 Indicator that the structure quality may be low 40 ALERT type 4 Improvement, methodology, query or suggestion 3 ALERT type 5 Informative message, check


Publication of your CIF

You should attempt to resolve as many as possible of the alerts in all categories. Often the minor alerts point to easily fixed oversights, errors and omissions in your CIF or refinement strategy, so attention to these fine details can be worthwhile. In order to resolve some of the more serious problems it may be necessary to carry out additional measurements or structure refinements. However, the nature of your study may justify the reported deviations from journal submission requirements and the more serious of these should be commented upon in the discussion or experimental section of a paper or in the "special_details" fields of the CIF. checkCIF was carefully designed to identify outliers and unusual parameters, but every test has its limitations and alerts that are not important in a particular case may appear. Conversely, the absence of alerts does not guarantee there are no aspects of the results needing attention. It is up to the individual to critically assess their own results and, if necessary, seek expert advice.

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PLATON version of 23/04/2026; check.def file version of 30/03/2026
Datablock KL_05_046_THF - ellipsoid plot

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